KRAS G12C inhibitor 16 ( —— )

产品货号. M32985 CAS No. 2349392-79-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

KRAS G12C inhibitor 16
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

KRAS G12C inhibitor 16 是一种有效的 KRAS G12C 抑制剂，IC50 为 97 nM，详细信息请参考专利文献 WO2019110751A1 中的化合物 39。
产品描述

KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 39, has an IC50 of 97 nM.
体外实验

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体内实验

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同义词

——
通路

Others
靶点

Other Targets
受体

Kras
研究领域

——
适应症

——

CAS Number

2349392-79-4
分子量

453.89
分子式

C24H21ClFN3O3
纯度

>98% (HPLC)
溶解度

——
SMILES

CC1=C2C(C=3N4[C@](CN(C(C=C)=O)CC4)(COC3C=N2)[H])=CC(Cl)=C1C5=C(F)C=CC=C5O
化学全称

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1. Jason Grant Kettle, et al. Tetracyclic compounds as inhibitors of g12c mutant ras protein, for use as anti-cancer agents. WO2019110751A1.

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